As a young BG gasman working in London I can remember the relief i felt when room sealed appliances became commonplace, this was because of the amount deaths from carbon monoxide I sadly witnesses or heard about due to OF appliances at the time.
Im sorry to say due to the lack of air pressure switches on HE boilers we have taken a step backwards and now again we are seeing needless deaths.
I would advise any gas fitter who doesn't have flue paronia to devolpe it quickly, only recently I got PPM readings in a child's bedroom from a flue that had disconnected in a void.
It's a good that more and more detectors are being fitted and that some manufactures are fitting carbon monoxide alarms in their appliances but even with this we have to be careful out there.