A bit late to this conversation. But here's my tuppence worth...
Combis can be great if you've only 1 shower, any more you'll either need to be good at organising a shower rota or go for stored hot water (open vented or unvented).
The next question for is what is your water supply like, as said earlier there's no point getting a 35kw combi if you've less than (ohh) 14 liters per min. If you've 9 litres per min, then a 24kw combi will be all you need, though you won't get that great a shower 'experience'. If getting the full use out of a 'rainfall' shower is essential, then you'll need a stored hot water system.
If you've a decent cold main supply (around 20 litres per min - check MI's) then unvented could be a useful solution. If the water supply is substantially less, then you'll be looking at an open vented system with a cold water storage tank in the attic.
There are more steps to go through, but the about is my starting point when trying to work out what would best fit my clients' needs