Remember not as experienced as you lot so don't shoot me down. Silly question. You are putting the combustion door back on with the four screws before you try to run the boiler aren't you?
Only if gas safe or some other inspector is there. If they are not then I don't worry about it too much.
Some boilers won't fire with the case removed (positive pressure cases mainly but also a few negative pressure cases) it's a pain having to put a case back on just to take it back off again.